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Tiny molecule will end trial and error era for depression treatment
6/9/2014 10:57:04 PM
Very small molecules miR-1202 are hard to find in the brains of those people who are suffering from depression. These molecules actually help the brains fight depression and lack of them actually causes depression.
This is going to help many people get right treatment. This will also help physicians in finding people who may be cured when treated by antidepressant medication.
Dr Gustavo Turecki, one of the lead authors of the report say, “Using samples from the Douglas Bell-Canada Brain Bank, we examined brain tissues from individuals who were depressed and compared them with brain tissues from psychiatrically healthy individuals”.
Dr Gustavo Turecki is a psychiatrist at the Douglas and professor in the Faculty of Medicine, Department of Psychiatry at McGill. The study has been jointly conducted by scientists at McGill University and the Douglas Institute.
Researchers are of the opinion that depression caused disability in many cases and notwithstanding the fact that there are ready treatments for the problem, finding right medication is the most important problem.
They say that physicians make numerous mistakes while treating such patients and many a times aggravate the problem. But the problem is going to be solved in the days to come. Turecki says, “We identified this molecule, a microRNA known as miR-1202, only found in humans and primates and discovered that it regulates an important receptor of the neurotransmitter glutamate”.
While detailing his finding further Turecki further says, “In our clinical trials with living depressed individuals treated with citalopram, a commonly prescribed antidepressant, we found lower levels in depressed individuals compared to the non-depressed individuals before treatment… Clearly, micro RNA miR-1202 increased as the treatment worked and individuals no longer felt depressed”. This is a huge development and will help millions of people suffering from depression.
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